Selected publications
Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice.
Hoffman M, Kyriazis ID, Lucchese AM, de Lucia C, Piedepalumbo M, Bauer M, Schulze PC, Bonios MJ, Koch WJ, Drosatos K. J Am Heart Assoc. 2019 May 21;8(10):e012260
Our study was selected for the Editorial
The Relationship Between KLF5 and PPARα in the Heart: It’s Complicated Peroxisome proliferator-activated receptor-γ activation prevents sepsis-related cardiac dysfunction and mortality in mice
Drosatos K, Khan RS, Trent CM, Jiang H, Son NH, Blaner WS, Homma S, Schulze PC, Goldberg IJ Circ Heart Fail. 2013, May;6(3):550-62 Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis while Oleic Acid-Induced Triglyceride Formation Prevents it.
Drosatos-Tampakaki Z, Drosatos K, Siegelin Y, Gong S, Khan S, Van Dyke T, Goldberg IJ, Schulze PC, Schulze-Späte U. J Bone Miner Res. 2013 Nov 23 Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology
Garcia-Arcos I, Hiyama Y, Drosatos K, Bharadwaj KG, Hu Y, Son NH, O'Byrne SM, Chang CL, Deckelbaum RJ, Takahashi M, Westerterp M, Obunike JC, Jiang H, Yagyu H, Blaner WS, Goldberg IJ J Biol Chem. 2013 May 17;288(20):14046-58 |
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Circulation. 2012 Jun 12;125(23):2844-53 Cardiac lipotoxicity: molecular pathways and therapeutic implications
Drosatos K, Schulze PC. Curr Heart Fail Rep. 2013 Jun;10(2):109-21 Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction
Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. J Biol Chem. 2011 Oct 21;286(42):36331-9 MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism
Iliopoulos D, Drosatos K, Hiyama Y, Goldberg IJ, Zannis VI. J Lipid Res. 2010 Jun;51(6):1513-23 Selected for the cover of the journal Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation
Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, Hu Y, Agarwal R, Yu S, Jiang H, Steinberg SF, Blaner WS, Koch WJ, Goldberg IJ.Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E489-99 Editor's choices |